NMR Spectroscopy at the Interface of Chemistry and Biology

Research in the Charlotte Held Gotfredsen Group focuses on using NMR spectroscopy as a tool to acquire structural knowledge at the interface of chemistry and biology. In our group, we investigate small molecules, oligosaccharides, natural products, and biologically relevant compounds to determine absolute molecular structures, probe ligand–protein Our, and support fragment-based drug discovery (FBDD) using ^{19F and} 1H NMR. Our work integrates chemical synthesis, structural biology, and method development to provide insights into molecular structure and function. The group is part of the NMR Spectroscopy unit of Organic Chemistry.