Sustainable and Therapeutic Chemical Biology
The research in the Katrine Qvortrup Group takes a multidisciplinary approach at the interface between chemistry and biology. We use synthetic molecules to systematically investigate the functions of genes, cells, and biochemical pathways in living systems. By combining organic synthesis, chemical biology, and molecular design, we seek to develop new strategies for understanding complex biological processes and creating therapeutic solutions. The group adheres to the Chemical Biology unit of Organic Chemistry.
Research
Second, we engage in hit optimization, combining the synthesis and screening of molecular compounds to develop new and effective treatments.
A third focus area is drug delivery to the brain, where we design barrier-shuttle mechanisms and chemical linkers that enable brain-selective drug release, minimizing side effects. Fourth, we work on antibody-based therapeutics, including chemical modification strategies to improve therapeutic properties and approaches for enabling antibodies to treat brain diseases. Finally, we pursue sustainable chemistry initiatives, such as developing indican-based, light-driven blue denim dyeing processes as environmentally friendly alternatives for the textile industry.
Across all areas, we integrate chemical synthesis, biological evaluation, and mechanistic understanding to drive innovation at the interface of chemistry and biology.