Nobelprisvinder forelæser på DTU

Professor Ei-ichi Negishi, Purdue University, som i 2010 modtog Nobelprisen i kemi, fortæller om The Magical Powers of d-Block Transition Metals på DTU i Lyngby i anledning af Kemiåret 2011.

Se invitationen her (.pdf)

Mere om forelæsningen - abstract

Magical Power of d-Block Transition Metals—Pd-Catalyzed Cross-Coupling and Zr-Catalyzed Asymmetric Carboalumination of Alkenes (ZACA) 

Until recently, the majority of the 24 d-block transition metals had been used as superior useful and sturdy materials. Half a century ago, a wide range of possibilities for use of d-block transition metals as catalysts for organic synthesis were recognized. These opportunities stem from mainly two fundamental properties of the d-block transition metals:  (1) simultaneous presence or availability of one or more filled-nonbonding (HOMO) and empty (LUMO) valence-shell orbitals, i.e. “carbene-like,” often as highly reactive and yet thermally stable species, (2) ability to undergo ready and reversible Redox processes under one-set of reaction conditions.

 
These properties have led to the development of a large number and widely ranging processes including critically important C–C bond formation reactions proceeding through:  (a) reduction elimination (ex. Pd-catalyzed cross-coupling), (b) carbometalation (ex. ZACA reaction), and (c) migration insertion (ex. carbonylation including “oxo” process).

 
In this lecture, a brief discussion of the Pd-catalyzed cross-coupling (mostly Negishi coupling) will be followed by a more detailed discussion of the Zr-catalyzed asymmetric carboalumination of alkenes (ZACA reaction). 

Læs mere om kemiåret 2011 her

Kontakt

Charlotte Malassé, DTU Kemi, cmal@kemi.dtu.dk