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2022
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Compounds having pseudomonas anti-biofilm properties

Givskov, Michael (Inventor) ; Tolker-Nielsen, Tim (Inventor) ; Andersen, Jens (Inventor) ; Holm-Jakobsen, Tim (Inventor) ; Hultqvist, Louise (Inventor) ; Nilsson, Carl (Inventor) ; Nielsen, Thomas (Inventor) ; Qvortrup, Katrine
Patent no.: WO2022043503, Date: 2020-08-27

Type: Patent

Status: Published     |    Year: 2022

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Small hydrophobic protein drug conjugates and uses thereof

Rosenkilde, Mette Marie (Inventor) ; Spiess, Katja (Inventor) ; Pedersen, Lola Julie Torz (Inventor) ; Henningsen, Maja Lind Nybo (Inventor) ; Qvortrup, Katrine
Patent no.: WO2022223837, Date:

Type: Patent

Status: Published     |    Year: 2022

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Small Molecule Drugs for Treatment of Alzheimer’s Diseases Developed on the Basis of Mechanistic Understanding of the Serotonin Receptors 4 and 6

Jansen, Charlotte Uldahl ; Qvortrup, Katrine
part of: Serotonin and the CNS - New Developments in Pharmacology and Therapeutics, 2022

Type: Book chapter (Peer reviewed)

Status: Published     |    Year: 2022     |    DOI: https://doi.org/10.5772/intechopen.96381

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Solid-phase synthesis and biological evaluation of piperazine-based novel bacterial topoisomerase inhibitors

Flagstad, Thomas ; Pedersen, Mette T. ; Jakobsen, Tim H. ; Felding, Jakob ; Tolker-Nielsen, Tim ; Givskov, Michael ; Qvortrup, Katrine ; Nielsen, Thomas E.
in: Bioorganic & Medicinal Chemistry Letters, vol: 57

Type: Journal article (Peer reviewed)

Status: Published     |    Year: 2022     |    DOI: https://doi.org/10.1016/j.bmcl.2021.128499

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Structural design of anthraquinone bridges in direct electron transfer of fructose dehydrogenase

Jansen, Charlotte Uldahl ; Yan, Xiaomei ; Ulstrup, Jens ; Xiao, Xinxin ; Qvortrup, Katrine
in: Colloids and Surfaces B: Biointerfaces, vol: 220

Type: Journal article (Peer reviewed)

Status: Published     |    Year: 2022     |    DOI: https://doi.org/10.1016/j.colsurfb.2022.112941

2021
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Identification of small molecules that interfere with c-di-GMP signaling and induce dispersal of Pseudomonas aeruginosa biofilms

Andersen, Jens Bo ; Hultqvist, Louise Dahl ; Jansen, Charlotte Uldahl ; Jakobsen, Tim Holm ; Nilsson, Martin ; Rybtke, Morten ; Uhd, Jesper ; Fritz, Blaine Gabriel ; Seifert, Roland ; Berthelsen, Jens ; Nielsen, Thomas Eiland ; Qvortrup, Katrine ; Givskov, Michael ; Tolker-Nielsen, Tim
in: npj Biofilms and Microbiomes, vol: 7, issue: 1

Type: Journal article (Peer reviewed)

Status: Published     |    Year: 2021     |    DOI: https://doi.org/10.1038/s41522-021-00225-4

 

Investigating GIPR (Ant)Agonism: A Structural Analysis of GIP and Its Receptor

Smit, Florent Xavier ; van der Velden, Wijnand Jacobus Cornelus ; Sheyma Kizilkaya, Hüsün ; Nørskov, Amalie ; Sparre-Ulrich, Alexander Hovard ; Qvortrup, Katrine ; Frimurer, Thomas Michael ; Rosenkilde, Mette M.
in: Structure, vol: 29, issue: 7, pages: 679-693.e6

Type: Journal article (Peer reviewed)

Status: Published     |    Year: 2021     |    DOI: https://doi.org/10.1016/j.str.2021.04.001

 

SAR study of 4-arylazo-3,5-diamino-1H-pyrazoles: identification of small molecules that induce dispersal of Pseudomonas aeruginosa biofilms

Jansen, Charlotte U. ; Uhd, Jesper ; Andersen, Jens B. ; Hultqvist, Louise D. ; Jakobsen, Tim H. ; Nilsson, Martin ; Nielsen, Thomas E. ; Givskov, Michael ; Tolker-Nielsen, Tim ; Qvortrup, Katrine M.
in: RSC Medicinal Chemistry, vol: 11, issue: 12, pages: 1868-1878

Type: Journal article (Peer reviewed)

Status: Published     |    Year: 2021     |    DOI: https://doi.org/10.1039/D1MD00275A