Prof. Dr. Rabah Boukherroub
Institute of Electronics, Microelectronics and Nanotechnology, Lille University, France
‘Applications of Photothermal Patches for Drug Delivery and Subcutaneous
Infection Treatment’
Organizer: Assoc. Prof. Qijin Chi, DTU Chemistry
Abstract
The controlled release of active principles over long-term periods has been recognized as one of the most promising biomedical technologies for the treatment of certain types of diseases. Medical conditions such as cancer, diabetes and chronic pain require medications that must be dosed intermittently on demand and over a long period of time. To address these issues, intelligent drug delivery systems for on-demand release are highly desirable. On-demand delivery of therapeutics plays an essential role in simplifying and improving patient care. The talk will overview our recent work on using graphene-based patches for controlled photothermal release of drugs under NIR (980 nm) irradiation and for the treatment of subcutaneous wound infections.
[1]. Transdermal skin patch based on reduced graphene oxide: a new approach for photothermal triggered permeation of ondansetron across porcine skin
Teodorescu et al. S. Szunerits, Journal of Controlled Release 245 (2017) 137-146
[2]. Photothermally triggered On-Demand Insulin Release from Reduced Graphene Oxide modified Hydrogels. Teodorescu et al. Journal of Controlled Release 246 (2017) 164–173
[3]. On demand electrochemical release of drugs from porous reduced graphene oxide modified flexible electrodes. Boulahneche et al. J. Mater. Chem. B, 2017, DOI: 10.1039/C7TB00687J
[4]. Highly efficient treatment of skin infections using flexible photothermal heating patches
Li et al. (2017)
Dr. Rabah Boukherroub received a PhD in chemistry from the University Paul Sabatier in Toulouse, France. He is currently a CNRS research director and a group leader at the Institute of Electronics, Microelectronics and Nanotechnology (IEMN), University of Lille, France. He is Associate Editor for ACS Applied Materials & Interfaces. He is also a guest Professor, China University of Petroleum, Qingdao, China. His research interests are in the area of functional materials, surface chemistry, and photophysics of semiconductor/metal nanostructures with emphasis on biosensors and photocatalysis, and development of new tools for studying molecular dynamics in vivo. He is a co-author of 440+ research publications with over 11000 citations and wrote 31 book chapters in subjects related to nanotechnology, materials chemistry, and biosensors. He has 11 patents or patents pending.