Pernille Harris

Pernille Harris

Associate Professor

DTU CHEMISTRY
Department of Chemistry

Kemi: Faculty
Physical and Biophysical Chemnistry: Protein and X-ray Crystallography
kemi-l-ledergruppe

Technical University of Denmark

Building 206, room 210

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2016
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The crystal structure of human dopamine  β-hydroxylase at 2.9 Å resolution

Vendelboe, Trine Vammen ; Harris, Pernille ; Zhao, Y. ; Walter, T. S. ; Harlos, K. ; El Omari, K. ; Christensen, Hans Erik Mølager
in: Science Advances (ISSN: 2375-2548), vol: 2, issue: 4, 2016

Type: Journal article (Peer reviewed)

Status: Published     |    Year: 2016     |    DOI: http://dx.doi.org/10.1126/sciadv.1500980

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Stabilization of Tryptophan Hydroxylase 2 by L-Phenylalanine Induced Dimerization

Tidemand, Kasper Damgaard ; Christensen, Hans Erik Mølager ; Hoeck, Niclas ; Harris, Pernille ; Boesen, Jane ; Peters, Günther H.J.
in: F E B S Open Bio (ISSN: 2211-5463), vol: 6, issue: 10, pages: 987-999, 2016

Type: Journal article (Peer reviewed)

Status: Published     |    Year: 2016     |    DOI: http://dx.doi.org/10.1002/2211-5463.12100

 

CYP1B1 Mutations in Individuals With Primary Congenital Glaucoma and Residing in Denmark

Grønskov, Karen ; Redó-Riveiro, Alba ; Sandfeld, Lisbeth ; Zibrandtsen, Nathalie ; Harris, Pernille ; Bach-Holm, Daniella ; Tümer, Zeynep
in: Journal of Glaucoma (ISSN: 1057-0829), vol: 25, issue: 12, pages: 926–930, 2016

Type: Journal article (Peer reviewed)

Status: Published     |    Year: 2016     |    DOI: http://dx.doi.org/10.1097/IJG.0000000000000581

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2015
 

Mutational analysis of divalent metal ion binding in the active site of class II α-mannosidase from sulfolobus solfataricus

Hansen, Dennis K. ; Webb, Helen ; Nielsen, Jonas Willum ; Winther, Jakob R. ; Willemoes, Martin ; Harris, Pernille
in: Biochemistry (ISSN: 0006-2960), vol: 54, issue: 11, pages: 2032-2039, 2015

Type: Journal article (Peer reviewed)

Status: Published     |    Year: 2015     |    DOI: http://dx.doi.org/10.1021/acs.biochem.5b00090

 

Bacillus halodurans Strain C125 Encodes and Synthesizes Enzymes from Both Known Pathways To Form dUMP Directly from Cytosine Deoxyribonucleotides

Oehlenschlæger, Christian Berg ; Løvgreen, Monika Nøhr ; Reinauer, Eva ; Lehtinen, Emilia ; Pind, Marie-Louise Lindberg ; Harris, Pernille ; Martinussen, Jan ; Willemoës, Martin
in: Applied and Environmental Microbiology (ISSN: 0099-2240), vol: 81, issue: 10, pages: 3395-3404, 2015

Type: Journal article (Peer reviewed)

Status: Published     |    Year: 2015     |    DOI: http://dx.doi.org/10.1128/AEM.00268-15

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Experimental and Theoretical Mechanistic Investigation of the Iridium-Catalyzed Dehydrogenative Decarbonylation of Primary Alcohols

Olsen, Esben Paul Krogh ; Singh, Thishana ; Harris, Pernille ; Andersson, Pher G. ; Madsen, Robert
in: Journal of the American Chemical Society (ISSN: 0002-7863), vol: 137, issue: 2, pages: 834-842, 2015

Type: Journal article (Peer reviewed)

Status: Published     |    Year: 2015     |    DOI: http://dx.doi.org/10.1021/ja5106943

 

Effects of thionation and fluorination on cis-trans isomerization in tertiary amides: An investigation of N -alkylglycine (Peptoid) rotamers

Engel-Andreasen, Jens ; Wich, Kathrine ; Laursen, Jonas S. ; Harris, Pernille ; Olsen, Christian Adam
in: Journal of Organic Chemistry (ISSN: 0022-3263), vol: 80, issue: 11, pages: 5415-5427, 2015

Type: Journal article (Peer reviewed)

Status: Published     |    Year: 2015     |    DOI: http://dx.doi.org/10.1021/acs.joc.5b00048

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Oligomerization of a Glucagon-like Peptide 1 Analog: Bridging Experiment and Simulations

Frederiksen, Tine Maja ; Sønderby, Pernille ; Ryberg, Line A. ; Harris, Pernille ; Bukrinski, Jens T. ; Scharff-Poulsen, Anne M. ; Elf-Lind, Maria Northved ; Peters, Günther H.J.
in: Biophysical Journal (ISSN: 0006-3495), vol: 109, issue: 6, pages: 1202-1213, 2015

Type: Journal article (Peer reviewed)

Status: Published     |    Year: 2015     |    DOI: http://dx.doi.org/10.1016/j.bpj.2015.07.051

 

Facile Large-Scale Synthesis of 5- and 6-Carboxyfluoresceins

Hammershøj, Peter ; Ek, Pramod Kumar ; Harris, Pernille ; Andresen, Thomas Lars ; Clausen, Mads Hartvig
in: European Journal of Organic Chemistry (ISSN: 1434-193X), vol: 2015, issue: 33, pages: 7301-7309, 2015

Type: Journal article (Peer reviewed)

Status: Published     |    Year: 2015     |    DOI: http://dx.doi.org/10.1002/ejoc.201501013